Import of animal viruses opposed after accident at laboratory

A new Overlay for Plaquing Animal Viruses

Animal Viruses: Molecular Biology

In this multi-author work, Mettenleiter and Sobrino have compiled 10 chapters that describe what is currently known about the molecular biology of some of the most interesting viruses of veterinary importance, from the tiny circovirus of pigs (1,800 nt of single-stranded DNA) to the highly complex African swine fever virus (≈200,000 nt pairs of double-stranded DNA). It is fi tting that the fi r...

Inactivation by gamma irradiation of animal viruses in simulated laboratory effluent.

Several animal viruses were treated with gamma radiation from a 60Co source under conditions which might be found in effluent from an animal disease laboratory. Swine vesicular disease virus, vesicular stomatitis virus, and blue-tongue virus were irradiated in tissues from experimentally infected animals. Pseudorabies virus, fowl plague virus, swine vesicular disease virus, and vesicular stomat...

Corrigendum: Influenza A viruses escape from MxA restriction at the expense of efficient nuclear vRNP import

The Acknowledgements section in this Article is incomplete. " We thank Richard Randall for providing A549 cells stably expressing MxA or shMxA, Georg Kochs for providing the NP-specific antibody and Geoffrey Chase, Georg Kochs and Peter Staeheli for critically reading of the manuscript. " should read: " We thank Richard Randall for providing A549 cells stably expressing MxA or shMxA, Georg Koch...

Influenza A viruses escape from MxA restriction at the expense of efficient nuclear vRNP import

To establish a new lineage in the human population, avian influenza A viruses (AIV) must overcome the intracellular restriction factor MxA. Partial escape from MxA restriction can be achieved when the viral nucleoprotein (NP) acquires the critical human-adaptive amino acid residues 100I/V, 283P, and 313Y. Here, we show that introduction of these three residues into the NP of an avian H5N1 virus...